Cthrc1 cancer

WebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. WebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple helix repeat containing 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTHRC1.

Collagen triple helix repeat containing 1 - Wikipedia

WebJun 20, 2024 · This study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Methods: CTHRC1 … WebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models … camp shelby famcamp https://mkbrehm.com

CTHRC1 promotes gastric cancer metastasis via HIF-1α/CXCR4 …

WebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer … WebCollagen triple helix repeat containing 1 (CTHRC1) is a secreted glycoprotein that decreases the deposition of collagen matrix and accelerates tumor metastasis. However, the relationship between CTHRC1 and the outcomes of head and neck squamous cell carcinoma (HNSCC) and tumor‑infiltrating lymphocytes remains unclear. In the present … WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. … camp shelby education center

CTHRC1 is a prognosis-related biomarker correlated with immune ...

Category:TGFβ and the Tumor Microenvironment in Colorectal Cancer

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Cthrc1 cancer

The Role of CTHRC1 in Regulation of Multiple Signaling and ... …

WebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, … WebMar 20, 2024 · CTHRC1 is widely upregulated in several solid tumors, including melanoma, gastrointestinal cancer, breast cancer, thyroid cancer, liver cancer, and pancreatic …

Cthrc1 cancer

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WebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In … WebOct 26, 2024 · The pan-cancer analysis showed that CTHRC1 was overexpressed in most tumors, and a significant correlation was observed between CTHRC1 expression and the …

WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and … WebSep 28, 2024 · CTHRC1, collagen triple helix repeat containing-1; CAF, cancer-associated fibroblast; CM, conditioned media. CAFs promote EMT alterations in BC cells by secreting CTHRC1 EMT is a recognized biological process that plays a key role in tumor metastasis, and is characterized by the loss of epithelial markers (such as E-cadherin) …

WebSep 23, 2024 · CTHRC1 may affect the occurrence and development of tumors by participating in the process of cell proliferation and migration, synthesis of type I collagen, and repair of damage to blood vessels in colorectal cancer, pancreatic cancer, HCC, etc. 6–9 CTHRC1 plays an important role in the pathogenesis of systemic lupus … WebApr 10, 2024 · The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is involved in cell migration, motility and invasion. The object of this study is to investigate the involvement of CTHRC1 in NSCLC invasion and metastasis. A proteomic analysis was …

WebJun 23, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) has been found to be upregulated in ESCC. However, its role in tumourigenesis and progression of ESCC …

WebNational Center for Biotechnology Information fis cup 2023WebJun 20, 2024 · CTHRC1 is a secretory glycoprotein that was discovered while differentially expressed genes were screened after severe arterial injury in rats. 6,7 Subsequently, researchers reported that CTHRC1 is … fiscus and ball pcWebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis. fiscus and ball pittsburghWebJul 19, 2024 · Abstract. Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated … camp shelby ms rv parkWebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, … camp shelby inrmpWebOct 6, 2024 · Ke, Z. et al. Overexpression of collagen triple helix repeat containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non … camp shelby mississippi infantry alcWebNov 14, 2024 · The high expression was confirmed by detecting the relative RNA expression of CTHRC1 in paired breast cancer and nontumor samples. The CTHRC1 transcriptional … fis cursos