WebJun 26, 2024 · Abstract. The Hippo pathway is a crucial signaling mechanism that inhibits the growth of cells and organs during development and in disease. When the Hippo … WebMar 15, 2024 · STX exposure promotes YAP1 cytoplasmic retention (A-B) Immunofluorescence analysis performed in N2a cells treated with STX. Scale bar, 10 …
Nuclear DDX3 expression predicts poor outcome in colorectal and …
WebMar 1, 2013 · A cytoplasm retention signal would, in theory, not be affected by these interventions, whereas we observed nuclear accumulation of Htt in the setting of inhibition of nuclear export. Given its high degree of evolutionary conservation, beyond the four amino acid NES motif, it is highly plausible that N17 contains overlapping, but distinct ... WebJul 19, 2004 · In this study, we present results about a novel function of tomato Hsp17.4-CII as cytoplasmic retention factor and corepressor of HsfA2. In fact, the functional state and intracellular distribution of HsfA2 is influenced by a network of proteins involving HsfA1, Hsp17-CI, and Hsp17-CII. RESULTS can loss of hearing cause memory loss
The complex relationship between TFEB transcription factor ...
WebMay 15, 2024 · Nucleo-cytoplasmic shuttling of transcription factors is used by the cell to control gene expression programs in response to the environment. Transcription factors exert their function primarily in the nucleus; however, under some conditions, they may be localized in the cytoplasm. WebJun 1, 2024 · Nucleo‐cytoplasmic shuttling of transcription factors is used by the cell to control gene expression programs in response to the environment. Transcription … Mitotic entry is determined by a threshold level of active cyclin-B1/CDK1 complex, also known as cyclin-B1/Cdc2 or the maturation promoting factor (MPF). Active cyclin-B1/CDK1 triggers irreversible actions in early mitosis, including centrosome separation, nuclear envelope breakdown, and spindle assembly. In vertebrates, there are five cyclin B isoforms (B1, B2, B3, B4, and … can loss of hearing be restored