WebApr 4, 2024 · Fezf2 is a selector gene able to regulate the expression of gene sets that collectively define mouse corticospinal motor neurons (CSMN). Ectopic Fezf2 expression is sufficient to redirect the fate of subventricular zone stem cells. Our findings establish a new, distinct physiological identity of Fezf2-expressing neurons within mature motor cortex. Web一、品系介绍:. Cre-ERT2小鼠是一类含有雌激素受体(estrogen receptor,ER)的配体结合区突变体(ERT)与Cre重组酶的融合蛋白表达的小鼠。. Cre-ERT2在无Tamoxifen诱 …
Genetically identified amygdala–striatal circuits for …
WebJun 3, 2024 · Seeking a non-invasive way to stimulate axon regeneration, we found that suprathreshold high-frequency repetitive transcranial magnetic stimulation activates the B-RAF canonical effectors MEK1/2 and requires MEK1/2 activity to promote corticospinal axon regeneration and sprouting after injury. WebJan 9, 2024 · These data reveal discrete bands of E2 and E3 cells that may relay information from the CSF to underlying neural circuits along the ventral midline. The ependymal epithelium lines the adult brain ventricles, where it plays key roles in cerebrospinal fluid (CSF) flow and brain homeostasis1,2. honda crv woodstock
Mutual regulation between Satb2 and Fezf2 promotes subcerebral ... - PNAS
WebFeb 22, 2024 · We used Fezf2-CreER mice driver line 41 to target ET neurons. Fezf2 is a gene expressed in the deep layers of the cortex and mainly in ET neurons 42,43. WebFinally, fezf2-GFP(hi) quiescent and fezf2-GFP(lo) proliferative NSCs are observed in postnatal mouse hippocampus, suggesting possible evolutionary conservation. Our results support a model in which fezf2 heterogeneity patterns gradient Notch activity among neighbors that is critical to balance NSC fate. WebOct 18, 2024 · The Fezf2-CreER or Fezf2-Flp knock-in mouse driver line, in which the expression of the inducible Cre recombinase (CreER) or Flp, respectively, is driven by … honda crv wrench light reset