Phosphatase tensin-type domain

WebMar 1, 2001 · Protein PHOSPHATASE AND TENSIN HOMOLOG 1 1 publication ( AtPTEN1 1 publication ) Gene names Name PTEN1 1 publication ORF names MUL8.80 Imported Ordered locus names At5g39400 Imported Organism names Organism Arabidopsis thaliana (Mouse-ear cress) Taxonomic identifier 3702 NCBI Taxonomic lineage WebMMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody; Mutated in multiple advanced cancers 1 antibody; Phosphatase and tensin homolog antibody; …

PTEN, a putative protein tyrosine phosphatase gene …

WebNov 4, 2024 · Also known as ATPEN2; phosphatase and TENsin homolog deleted on chromosome ten 2A; PTEN 2; PTEN2A Summary Encodes a phosphatase with low in vitro tyrosine phosphatase activity that is capable of dephosphorylating in vitro the 3'phosphate group of PI3P, PI (3,4)P2, and PI (3,5)P2 and may be an effector of lipid signaling. NEW … WebJul 5, 2005 · Domain: 431-573: C2 tensin-type InterPro annotation. BLAST Add. ... PTHR12305 PHOSPHATASE WITH HOMOLOGY TO TENSIN 1 hit; PTHR12305:SF60 … side effects of xyzal https://mkbrehm.com

The significance of PTEN

WebMar 21, 2024 · TNS3 (Tensin 3) is a Protein Coding gene. Diseases associated with TNS3 include Thyroid Tumor and Primary Syphilis . Among its related pathways are MET promotes cell motility and Signaling by Receptor Tyrosine Kinases . Gene Ontology (GO) annotations related to this gene include phosphatase activity . An important paralog of this gene is … WebSMART: PTEN_C2 domain annotation PTEN_C2 C2 domain of PTEN tumour-suppressor protein There are 6056 PTEN_C2 domains in 6045 proteins in SMART's nrdb database. Click on the following links for more information. Evolution (species in which this domain is found) Cellular role (predicted cellular role) Structure (3D structures containing this domain) WebAug 26, 2024 · The importance of phosphatase and tensin homolog deleted on chromosome ten ( PTEN) in tumorigenesis is underscored by its frequent mutations, … side effects of yacella

TNS3 Gene - GeneCards TENS3 Protein TENS3 Antibody

Category:PTEN Gene - GeneCards PTEN Protein PTEN Antibody

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Phosphatase tensin-type domain

Human Gene TNS3 (ENST00000311160.14) from GENCODE V38

WebIPR014020 - Tensin_phosphatase_C2-dom Pfam Domains: PF08416 - Phosphotyrosine-binding domain PF10409 - C2 domain of PTEN tumour-suppressor protein PF00017 - SH2 … WebChain A, Tensin-like C1 domain-containing phosphatase (human) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW …

Phosphatase tensin-type domain

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WebEnables lipid phosphatase activity. Acts upstream of or within several processes, including lifelong otolith mineralization; negative regulation of angiogenesis; and phosphatidylinositol dephosphorylation. Predicted to be located in PML body and cytoplasm.

WebContains 1 phosphatase tensin-type domain. 结构域 The C2 domain binds phospholipid membranes in vitro in a Ca(2+)-independent manner; this binding is important for its tumor suppressor function. WebApr 3, 2024 · PTEN phosphatase and tensin homolog Gene ID: 5728, updated on 3-Apr-2024 Gene type: protein coding Also known as: BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; …

WebTensins constitute an eukaryotic family of lipid phosphatases that are defined by the presence of two adjacent domains: a lipid phosphatase domain and a C2-like domain. The … WebDescription: Homo sapiens transmembrane phosphatase with tensin homology (TPTE), transcript variant 1, mRNA. (from RefSeq NM_199261) RefSeq Summary (NM_199261): …

WebBreast cancer has been attributed to be the second most common malignancy in females worldwide after skin cancer associated with a significantly high mortality rate. Tumor suppressor genes have an indispensable role in maintaining genomic integrity

WebJan 2, 2024 · Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) encodes a 403-amino acid protein with an amino-terminal domain that shares sequence homology with the actin-binding protein tensin and the putative tyrosine-protein phosphatase auxilin.Crystal structure analysis of PTEN has revealed a C2 domain that binds to … side effects of xyngWebProteins known to contain a phosphatase and a C2 tensin-type domain are listed below: Tensin, a focal-adhesion molecule that binds to actin filaments. It may be involved in cell … the plaice fish and chips winchesterWebMar 28, 1997 · In preliminary screens, mutations of PTEN were detected in 31% (13/42) of glioblastoma cell lines and xenografts, 100% (4/4) of prostate cancer cell lines, 6% (4/65) … side effects of yeast infection creamWebMar 28, 2024 · Among them, Src homology region 2 domain containing phosphatase-1 (SHP1), phosphatase and tensin homolog deleted on chromosome 10 (PTEN), and MAP kinase phosphatase 1 (MKP1) act as negative regulators in OCs. SHP1 is a non-receptor-type PTP, which is a product of Ptpn6. side effects of yonsaWebJul 27, 2015 · PTEN is composed of four structural domains [PIP2-binding domain (aa 1–13), a catalytic tensin-type phosphatase domain (aa 14–185), a C2 tensin-type domain, which binds phospholipids (aa 190–350), the carboxy-terminal tail of the protein (aa 350–400), and a PDZ-binding domain (aa 401–403). the plaice fish and chips oswestryWebFeb 17, 2024 · Tensin was first reported in 1991 as an actin-binding focal-adhesion protein containing a Src homology 2 (SH2) domain, a newly identified binding motif specific for phosphotyrosine (pTyr) at the time, suggesting an interesting role of tensin in bridging signal transduction pathways with the cytoskeletal networks ( Davis et al., 1991 ). theplaidhorse.comWebJan 1, 2009 · Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor and bi-functional lipid and protein phosphatase. We report that the metabolic regulator pyruvate dehydrogenase kinase1 (PDHK1) is a synthetic-essential gene in PTEN-deficient cancer and normal cells. the plaid elephant danville ky